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| 產(chǎn)地 | France |
| 品牌 | AntibodySystem |
| 保存條件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -101°C long term. |
| 貨號 | DHD72201 |
| 用途 | 類似物，陽性對照抗體 |
| 應(yīng)用范圍 | 類似物，陽性對照抗體 |
| 抗原來源 | Mammalian cells |
| 保質(zhì)期 | 1 year |
| 抗體名 | Research Grade Varlilumab |
| 是否單克隆 | 是 |
| 克隆性 | 是 |
| 靶點(diǎn) | 1F5 |
| 適應(yīng)物種 | Human |
| 形態(tài) | Liquid |
| 宿主 | 是 |
| 標(biāo)記物 | Unconjugate |
| 包裝規(guī)格 | 100ug |
| 亞型 | IgG |
| 標(biāo)識物 | Unconjugate |
| 濃度 | 1mg/ml% |
| 免疫原 | Human |
| 是否進(jìn)口 | 是 |
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Varlilumab is a fully human monoclonal antibody (mAb) that targets CD27, a critical molecule in the activation pathway of lymphocytes. Like CD40, CD27 can be effectively manipulated with activating antibodies to induce potent anti-tumor responses, and may result in less toxicities due to its restricted expression and regulation. Varlilumab is a novel, first-in-class, agonist CD27 antibody that stimulates the CD27 pathway, which results in T-cell activation and antitumor activity in tumor models. This first-in-human, dose-escalation and expansion study evaluated the safety, pharmacology, and activity of varlilumab in patients with advanced solid tumors.
DHD72201
Homo sapiens
Human
Liquid
PBS buffer pH 7.4
0.63 mg/ml
>95%
Monoclonal
IgG1-kappa
Research Grade Varlilumab Biosimilar
CD27L receptor,TNFRSF7,T14,CD27 antigen,Tumor necrosis factor receptor superfamily member 7,CD27,T-cell activation antigen CD27
Protein A or G purified from cell culture supernatant.
Please contact with the lab for this information.
Mammalian cells
P26842
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
1F5, CDX-1127, CAS: 1393344-72-3
For research use only. Not suitable for clinical or therapeutic use.
Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of professionals from top industrial companies and research institutes. The collective scientific and technical experiences in our team have brought breaking throughs in multiple product developments, including recombinant antibodies, recombinant proteins, biosimilar, RUO ELISA kits and other related products. By working with talented researchers and technicians, AntibodySystem continues to upgrade product qualities and lower the overall cost, offering accountable and affordable solutions for biolabs all over the world. Since its establishment, AntibodySystem has built long term and stable collaborations with academia, pharmaceutical industry, biotech companies and research hospitals, supporting their R&D by AntibodySystem's bioreagents with excellent data accuracy and reproducibility.
AntibodySystem由具有30多年蛋白抗體開發(fā)經(jīng)驗(yàn)的 創(chuàng)立于法國,專注于生命科學(xué)和生物制藥領(lǐng)域研究,總部位于法國斯特拉斯堡市。AntibodySystem自主開發(fā)了高效、高產(chǎn)的真核重組表達(dá)系統(tǒng),利用該系統(tǒng)生產(chǎn)了高質(zhì)量的重組蛋白、抗體產(chǎn)品。目前產(chǎn)品包括藥物靶點(diǎn)蛋白以及對照抗體藥物、Invivo功能性抗體、SAA系列流式抗體、PEG抗體、磷酸化抗體、抗小分子抗體、ADA抗體、PK&ADA ELISA試劑盒。
普健生物作為AntibodySystem在亞洲區(qū)授權(quán) ,致力于為廣大科研工作者提供 的產(chǎn)品服務(wù)。
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