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Research Grade Etokimab ( 艾托奇單抗 )
  • 品牌:AntibodySystem
  • 產(chǎn)地:France
  • 型號:100ug
  • 貨號:DHB74001
  • cas:2022981-44-6
  • 發(fā)布日期: 2022-10-18
  • 更新日期: 2024-10-25
產(chǎn)品詳請
產(chǎn)地 France
品牌 AntibodySystem
保存條件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -133°C long term.
貨號 DHB74001
用途 類似物,陽性對照抗體
應(yīng)用范圍 類似物,陽性對照抗體
抗原來源 Mammalian cells
保質(zhì)期 1 year
抗體名 Research Grade Etokimab
是否單克隆
克隆性
靶點 ANB020
適應(yīng)物種 Human
形態(tài) Liquid
宿主
標記物 Unconjugate
包裝規(guī)格 100ug
亞型 IgG
標識物 Unconjugate
濃度 1mg/ml%
免疫原 Human
是否進口

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Description

ANB020, now called etokimab, is currently in phase 2a testing in eczema, which is also known as atopic dermatitis. Scientists from the Medical Research Council Human Immunology Unit at the University of Oxford released data from 12 patients showing that 83% who were treated with etokimab reported a reduction in disease severity after 29 days. Etokimab, an anti-IL-33 biologic, has previously demonstrated a good safety profile and favorable pharmacodynamic properties in many clinical studies. Etokimab is designed to block interleukin-33 (IL-33), an immune-signaling molecule. In peanut allergy, the body overreacts to peanuts as IL-33 activates an antibody called immunoglobin E. These antibodies cause allergic response such as mouth itchiness, hives, breathing difficulties and potentially fatal anaphylactic shock.

Catalog No.

DHB74001

Host species

Humanized

Species reactivity

Human

Storage buffer

PBS buffer pH 7.5

Purity

>95%

Clonality

Monoclonal

Isotype

IgG1-kappa

Applications

Research Grade Etokimab Biosimilar

Target

NF-HEV,IL-1F11,C9orf26,IL-33,Interleukin-1 family member 11,IL33,Nuclear factor from high endothelial venules,NFHEV,Interleukin-33,IL1F11

Purification

Protein A or G purified from cell culture supernatant.

Endotoxin level

Please contact with the lab for this information.

Expression system

Mammalian cells


Accession

O95760

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

Alternative Names

ANB020, CAS: 2022981-44-6,IL33

Note

For research use only. Not suitable for clinical or therapeutic use.


Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of professionals from top industrial companies and research institutes. The collective scientific and technical experiences in our team have brought breaking throughs in multiple product developments, including recombinant antibodies, recombinant proteins, biosimilar, RUO ELISA kits and other related products. By working with talented researchers and technicians, AntibodySystem continues to upgrade product qualities and lower the overall cost, offering accountable and affordable solutions for biolabs all over the world. Since its establishment, AntibodySystem has built long term and stable collaborations with academia, pharmaceutical industry, biotech companies and research hospitals, supporting their R&D by AntibodySystem's bioreagents with excellent data accuracy and reproducibility.

AntibodySystem由具有30多年蛋白抗體開發(fā)經(jīng)驗的 創(chuàng)立于法國,專注于生命科學和生物制藥領(lǐng)域研究,總部位于法國斯特拉斯堡市。AntibodySystem自主開發(fā)了高效、高產(chǎn)的真核重組表達系統(tǒng),利用該系統(tǒng)生產(chǎn)了高質(zhì)量的重組蛋白、抗體產(chǎn)品。目前產(chǎn)品包括藥物靶點蛋白以及對照抗體藥物、Invivo功能性抗體、SAA系列流式抗體、PEG抗體、磷酸化抗體、抗小分子抗體、ADA抗體、PK&ADA ELISA試劑盒。


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