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Research Grade Glofitamab ( 格菲妥單抗 )
  • 品牌:AntibodySystem
  • 產(chǎn)地:France
  • 型號:100ug
  • 貨號:DHC90714
  • cas:2229047-91-8
  • 發(fā)布日期: 2022-10-18
  • 更新日期: 2024-10-24
產(chǎn)品詳請
產(chǎn)地 France
品牌 AntibodySystem
保存條件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -310°C long term.
貨號 DHC90714
用途 類似物,陽性對照抗體
應(yīng)用范圍 類似物,陽性對照抗體
抗原來源 Mammalian cells
保質(zhì)期 1 year
抗體名 Research Grade Glofitamab
是否單克隆
克隆性
靶點 Bispecific
適應(yīng)物種 Human
形態(tài) Liquid
宿主
標記物 Unconjugate
包裝規(guī)格 100ug
亞型 IgG
標識物 Unconjugate
濃度 1mg/ml%
免疫原 Human
是否進口

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Description

Glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells. Glofitamab is an investigational, T-cell bispecific antibody with a distinctive design that features 2 Fab arms for binding CD20 on B cells, along with 1 Fab arm for binding CD3 on T cells. The CD3 binding arm is fused directly to one of the CD20-binding arms in a head-to-tail fashion via a short flexible linker.

Catalog No.

DHC90714

Host species

Humanized

Species reactivity

Human

Concentration

1mg/ml

Purity

>95%


Clonality

Monoclonal


Isotype

IgG1-kappa-lambda

Applications

Research Grade Glofitamab Biosimilar

Target

Bispecific,B-lymphocyte surface antigen B1,Membrane-spanning 4-domains subfamily A member 1,MS4A1,Leukocyte surface antigen Leu-16,B-lymphocyte antigen CD20,Bp35,CD20,T3E,T-cell surface antigen T3/Leu-4 epsilon chain,CD3e,T-cell surface glycoprotein CD3 epsilon chain

Purification

Protein A or G purified from cell culture supernatant.

Endotoxin level

Please contact with the lab for this information.

Expression system

Mammalian cells

Accession

P11836 & P07766

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

Alternative Names

Bispecific, CD20-TCB (2:1), RG-6026, CAS: 2229047-91-8

Note

For research use only. Not suitable for clinical or therapeutic use.


Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of professionals from top industrial companies and research institutes. The collective scientific and technical experiences in our team have brought breaking throughs in multiple product developments, including recombinant antibodies, recombinant proteins, biosimilar, RUO ELISA kits and other related products. By working with talented researchers and technicians, AntibodySystem continues to upgrade product qualities and lower the overall cost, offering accountable and affordable solutions for biolabs all over the world. Since its establishment, AntibodySystem has built long term and stable collaborations with academia, pharmaceutical industry, biotech companies and research hospitals, supporting their R&D by AntibodySystem's bioreagents with excellent data accuracy and reproducibility.

AntibodySystem由具有30多年蛋白抗體開發(fā)經(jīng)驗的 創(chuàng)立于法國,專注于生命科學(xué)和生物制藥領(lǐng)域研究,總部位于法國斯特拉斯堡市。AntibodySystem自主開發(fā)了高效、高產(chǎn)的真核重組表達系統(tǒng),利用該系統(tǒng)生產(chǎn)了高質(zhì)量的重組蛋白、抗體產(chǎn)品。目前產(chǎn)品包括藥物靶點蛋白以及對照抗體藥物、Invivo功能性抗體、SAA系列流式抗體、PEG抗體、磷酸化抗體、抗小分子抗體、ADA抗體、PK&ADA ELISA試劑盒。


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