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Research Grade Motavizumab ( 莫維組單抗 )
  • 品牌:AntibodySystem
  • 產(chǎn)地:France
  • 型號(hào):100ug
  • 貨號(hào):DVV02803
  • cas:677010-34-3
  • 發(fā)布日期: 2022-10-18
  • 更新日期: 2024-10-24
產(chǎn)品詳請(qǐng)
產(chǎn)地 France
品牌 AntibodySystem
保存條件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -350°C long term.
貨號(hào) DVV02803
用途 類似物,陽(yáng)性對(duì)照抗體
應(yīng)用范圍 類似物,陽(yáng)性對(duì)照抗體
抗原來(lái)源 Mammalian cells
保質(zhì)期 1 year
抗體名 Research Grade Motavizumab
是否單克隆
克隆性
靶點(diǎn) MEDI-524
適應(yīng)物種 Human
形態(tài) Liquid
宿主
標(biāo)記物 Unconjugate
包裝規(guī)格 100ug
亞型 IgG
標(biāo)識(shí)物 Unconjugate
濃度 1mg/ml%
免疫原 Human
是否進(jìn)口

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Description

Motavizumab (MEDI-524, NUMAX, NISTmAb) is a second generation monoclonal antibody (mAb) derived from palivizumab (Synagis) using affinity maturation techniques. Motavizumab is currently undergoing US Food and Drug Administration review as a treatment for respiratory syncytial virus (RSV) prophylaxis.

It has been evaluated in large-scale clinical studies, and has demonstrated efficacy in reducing the disease burden of RSV in high-risk infant populations.Motavizumab (MEDI-524, NUMAX, NISTmAb) has higher affinity and a longer half-life, was effective in reducing RSV hospitalization in high-risk full-term infants in the US, but was not licensed due to safety concerns (allergic reactions) .

Catalog No.

DVV02803


Host species

Humanized

Species reactivity

HRSV-A

Form

Liquid


Storage buffer

0.01M PBS, pH 7.4.


Concentration

1.36 mg/ml

Purity

>95% by SDS-PAGE.

Clonality

Monoclonal

Isotype

IgG1, kappa

Applications

Research Grade Motavizumab Biosimilar

Target

F,Fusion glycoprotein F0

Purification

Protein A or G purified from cell culture supernatant.

Endotoxin level

Please contact with the lab for this information.

Expression system

Mammalian

Accession

P03420

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

Alternative Names

MEDI-524,NUMAX, NISTmAb, CR9503, CAS: 677010-34-3, Human Respiratory Syncytial Virus (HRSV)

Note

For research use only. Not suitable for clinical or therapeutic use.


Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of professionals from top industrial companies and research institutes. The collective scientific and technical experiences in our team have brought breaking throughs in multiple product developments, including recombinant antibodies, recombinant proteins, biosimilar, RUO ELISA kits and other related products. By working with talented researchers and technicians, AntibodySystem continues to upgrade product qualities and lower the overall cost, offering accountable and affordable solutions for biolabs all over the world. Since its establishment, AntibodySystem has built long term and stable collaborations with academia, pharmaceutical industry, biotech companies and research hospitals, supporting their R&D by AntibodySystem's bioreagents with excellent data accuracy and reproducibility.

AntibodySystem由具有30多年蛋白抗體開(kāi)發(fā)經(jīng)驗(yàn)的 創(chuàng)立于法國(guó),專注于生命科學(xué)和生物制藥領(lǐng)域研究,總部位于法國(guó)斯特拉斯堡市。AntibodySystem自主開(kāi)發(fā)了高效、高產(chǎn)的真核重組表達(dá)系統(tǒng),利用該系統(tǒng)生產(chǎn)了高質(zhì)量的重組蛋白、抗體產(chǎn)品。目前產(chǎn)品包括藥物靶點(diǎn)蛋白以及對(duì)照抗體藥物、Invivo功能性抗體、SAA系列流式抗體、PEG抗體、磷酸化抗體、抗小分子抗體、ADA抗體、PK&ADA ELISA試劑盒。


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如果您對(duì)我們的產(chǎn)品感興趣,請(qǐng)聯(lián)系027-65279366。

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