2024-07-17
中文名稱(chēng):CD120b/TNFRSF1B/TNFR2蛋白抗體
一 、產(chǎn)品描述
TNFR2(腫瘤壞死因子受體超家族成員1B)是一種對TNFSF2/TNF-α具有高親和力的受體。它對同源三聚體TNFSF1/淋巴毒素-α的親和力要低得多。TRAF1/TRAF2復合物將凋亡抑制因子BIRC2和BIRC3募集到TNFRSF1B/TNFR2。TNFR2介導TNF-α的大部分代謝作用。
二 、產(chǎn)品詳情
貨號 |
DHD38905 |
宿主 |
Human |
適用物種 |
Human |
形式 |
Liquid |
存儲緩沖區 |
0.01M PBS, pH 7.4. |
濃度 |
1 mg/ml |
純度 |
>95% by SDS-PAGE. |
克隆 |
Monoclonal |
同型 |
IgG1-kappa |
應用 |
Research Grade Biosimilar |
內毒素水平 |
Please contact with the lab for this information. |
UniProt: |
P20333 |
注意 |
僅供研究使用 |
別名 |
TNF-R2, TNFR-II, p80 TNF-alpha receptor, Etanercept, TNFBR, TBP-2, TBPII, Tumor necrosis factor receptor superfamily member 1B, CD120b, p75, TNFRSF1B, Tumor necrosis factor receptor 2, TNF-RII, TNFR2, Tumor necrosis factor receptor type II,HFB200301 |
穩定性和儲存 |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term. |
三、 已發(fā)表文獻
TNFRSF1B Is Associated with ANCA in IBD. PMID: 27104820 |
TNFRSF1B and TNF Variants Are Associated With Differences in Levels of Soluble Tumor Necrosis Factor Receptors in Patients With Severe COVID-19. PMID: 35294530 |
TNFRSF1B Gene Variants in Clinicopathological Aspects and Prognosis of Patients with Cutaneous Melanoma. PMID: 38474115 |
TNFRSF1B in genetic predisposition to clinical neuropathy and effect on HDL cholesterol and glycosylated hemoglobin in type 2 diabetes. PMID: 11315843 |
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