貨號

DHE85608

宿主

Human

適用物種

Human

形式

Liquid

存儲緩沖區

0.01M PBS, pH 7.4

濃度

1 mg/ml

純度

>95% by SDS-PAGE

克隆

Monoclonal

同型

IgG1, kappa

應用

Research Grade Biosimilar

內毒素水平

Please contact with the lab for this information.

UniProt：

P51685

注意

僅供研究使用

別名

CD198，CCR8，LM108

穩定性和儲存

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory. PMID: 35140181

S-531011, a Novel Anti-Human CCR8 Antibody, Induces Potent Antitumor Responses through Depletion of Tumor-Infiltrating CCR8-Expressing Regulatory T Cells. PMID: 37420296

CCR8 as a Therapeutic Novel Target: Omics-Integrated Comprehensive Analysis for Systematically Prioritizing Indications. PMID: 38001911

CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function. PMID: 33838058

CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin. PMID: 29427415